Prevalence of Hepatitis B and C Infections among Pregnant Women at Dalhatu Araf Specialist Hospital Lafia, Nasarawa State Nigeria
Journal of Advances in Microbiology,
Page 13-18
DOI:
10.9734/jamb/2022/v22i730470
Abstract
Hepatitis infections are global public health concern more especially hepatitis B virus (HBV) and hepatitis C virus (HCV) infections which can easily be transmitted from mothers to newborn babies through contact with body secretions. This research was conducted to investigate the prevalence of Viral Hepatitis B and C infections among pregnant women in Dalhatu Araf Specialist Hospital Lafia, Nasarawa State. Cross sectional study design was carried out from January 2017 to December 2017 among 374 pregnant women. Blood sample was collected from each pregnant woman and screened using enzyme-linked immunosorbent assay (ELISA) kit produced by Nantong Diagnos Biotechnology Co., Ltd., China. Overall prevalence infections of viral hepatitis B and C among the participant was 35(9.4%) and 18(4.8%) respectively. Hepatitis B prevalence was higher than Hepatitis C (P>0.05). Some of the pregnant women were found to be multi-gravida patients ranged from 20-29 years of age with prevalence of 9.6% HBV and 5.1% HCV (P> 0.05). The findings of this research suggest need to initiate public awareness to reduce disease load and transmission; immunization to all pregnant women and their newborn babies.
Keywords:
- HBV
- HCV
- antenatal
- pregnant women
How to Cite
References
Alavian S.M, Hajarizadeh B, Ahmadzad- ASL M, Kabir A, and Bagheri-Lankarani K. Hepatitis B virus infection in Iran: A Systematic Review Hepat Mon. 2008;8(4): 281-94.
Saraswathi KS, Aljabri F. The study of prevalence of Hepatitis B surface antigen during pregnancy in tertiary care hospital, South India. Der Pharmacial Lettre. 2012;4(3):983-5.
Safir A, Levy A, Sikuler E, Sheiner E. Maternal hepatitis B virus on hepatitis C carrier status as an independent risk factor for adverse perinatal outcome. Liver International. 2010;30(5):765-770.
Poro Lujaj J, Majdtadeh R. Prevalence of chronic Hepatitis B infection in Iran. Iran J. Epidemology. 2009;4(3):1-8.
Fernandes C.N, Alves Mde M, de Souta ML, Machado GA, Couto G and Evangelista RA. prevalence of seropositivity for Hepatitis B and C in pregnant women. Rev Esc Enfern USP. 2014;48(1):91-8.
Bzowej NH. Hepatitis B Therapy in pregnancy Curr Hepat Rep. 2010;9(4): 197-204.
Jonas MM. Hepatitis B and pregnancy: an underestimated issue Liver Int. 2009;29:133-9.
Ali HS, Memon MA. Prevalence of Hepatitis B infection in pregnant women in a tertiary care hospital. Journal of Infectious Disease Pakistian. 2007;2:35–38.
Luka SA, Ibrahim MB, Iliya S. Seroprevalence of Hepatitis B surface antigen among pregnant women attending antenatal clinic in Ahmadu Bello University Teaching Hospital Zaria. Nig J Paras. 2008;29:38–41.
Averhoff FN, Glass N, Holtzman D. Global Burden of Hepatitis C: Considerations for Healthcare Providers in the United State, Clinical Infectious Diseases. 2012;55(1):10-15.
Blach S, Zenzem S, Manus M. Global Prevalence and genotype distribution of hepatitis C virus infection. The Lancent Gastrozenterology and Hepatology. 2017;2(3):161-176.
Arshad M, Elkamary SS, Jhaveri. Hepatitis C virus infection during pregnancy and the newborn period. J of Viral Hepatitis. 2011;18(4):229-236.
Essan AJ, Omisakin CT, Ojo-bola T, Owoseni MF, Fasakin KA, Ogunleye AA. Seroprevalence of Hepatitis B and C Virus Co-infection among Pregnant Women in Nigeria. American Journal of Biomedical Research. 2014;2(1):11-15.
World Health Organization. Hepatitis C: Fact Sheet No. 2015;164.
World Health Organization. Organization Hepatitis B Factsheet, World Health Organization, Geneva, Switzerland.
Reddick KLB, Jhaveri R, Gandhi M, James AH, Swamy GK. Pregnancy outcomes associated with viral hepatitis. Journal of Viral Hepatitis. 2011;18 (7):394-398.
Connell LE, Salihu HM, Salemi JL, August EA, Weldeselasse H, Mbah AK. Maternal hepatitis B and hepatitis C carrier status and perinatal outcomes. Liver International. 2011;31(8): 1163-1170.
Krejcie, Morgan. Determining sample size for research activities. Educational and Psychological Measurement. 1970;30: 607-610.
World Health Organization. Prevention and control of viral hepatitis infection; framework for global action, World Health Organization, Geneva, Switzerland; 2012.
Dawaki SS, Kawo AH. Seroprevalence of Hepatitis B surface antigen (HBsAg) in pregnant women attending an urban maternity hospital in Kano, Nigeria. Nig J Microbiol. 2006;20:705–709.
Ejele Q, Ojulu A. The prevalence of Hepatitis B surface antigen among prospective blood donors and patients in Portharcourt, Nigeria. Niger Med. 2004;(13):336–338.
Uneke CJ, Ogbu O, Iyama PU. Prevalence of HBsAg among blood donors and HIV- infected patients in Jos, Nigeria. Afr Health. 2005;5:58–59.
Ebie JC, Pela OA. Some socio-cultural aspects of the problem of drug abuse in Nigeria. Drug Alc Dep. 2006;8:301–306.
Strickland GT. Hepatitis C in developing countries. Postgrad Doc (Africa). 2002;24:18–20.
Otegbayo JA, Fasola FO, Abaja A. Prevalence of Hepatitis B surfaceantigen (HBsAg) and Hepatitis B envelope antigens (HBeAg), risk factorsof viral acquisition and transminase among blood donors in Ibadan, Nigeria. Tropical Gasteroenterology. 2003;(24):217–226.
Hayder I, Ahmed W, Alam SE. Comparison of Different ICT Kits for HBsAg and Anti HCV Using Gold Standard ELISA. Pakistan Medical Journal. 2012;51(3):72–6.
Awan SN, Nayyar S, Ashraf N. (2006).Obstetrics and perinatal outcome; Risk factors for Hepatitis B and C transmission. Professional Medical Journal. 2006;(13):511–516.
Egah DZ, Banwat EB, Audu ES. Hepatitis B surface antigen, Hepatitis C and HIV antibodies in a low risk blood donor group, Nigeria. East Med Health J. 2007;13:211–215.
Maurenen Jonal M. Hepatitis B Pregnancy: Underestimated Issue. Liv Int. 2009;(1):33-139.
Sookoian S. Liver disease during pregnancy: acute viral hepatitis. Ann Hepatol. 2006;5(3):231-6.
Tomar S, Chourey P, Urhekar AD, Kore A. Study of Incidence of Hepatitis B and A Comparative Study to Check the Specificity and Sensitivity of Immunochromatographic Technique CT with Enzyme Linked Immunosorbant Assay (ELISA) for Hepatitis B Infection. 2012;341-346.
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